Mbagathi and Pumwani hospitals will also benefit from the project the county is running together with other non-governmental sponsors.
City Hall has embarked on modernising Mama Lucy Hospital and revamping other health facilities within the county, Governor Mike Sonko has said.
The programmes, whose cost Mr Sonko, did not reveal are aimed at improving access and raising standards.
Mbagathi and Pumwani hospitals will also benefit from the project the county is running together with other non-governmental sponsors.
Mama Lucy will have a new oxygen plant, 20 modern theatre beds, which are a donation, and two radiology machines to be supplied under competitive bids announced this week.
The bid winners should be known in the next two weeks, the governor has said.
These will be added to an MRI machine, portable X-Ray and mammogram machines, and dental equipment that are on site.
Mr Sonko said on Wednesday that the planned upgrade is a partnership between the county and Unicef, Hewa Tele and a UK NGO.
He said the steps are part of his vote-hunt pledges during campaigns in the run-up to the last general elections.
“We know the complaints from the public. I am appealing for the public to give me 14 days to transform the facility,” said Mr Sonko.
To ease congestion, he said Mama Lucy will revive the construction of a 60-bed ward block that stalled three years ago.
The hospital is also set to have a mortuary that can hold 70 bodies while three stalled ambulances will be repaired and new ones acquired, he said.
Mbagathi Hospital is set to have a standby generator and a renal unit.
The county is liaising with the Health secretary Cleopa Mailu on how to increase the number of clinics so that each of the 85 wards in Nairobi gets a mobile facility.
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